Molly affects target users' brains

Molly, a slang term used to describe pure MDMA (3,4-methylenedioxymethamphetamine), is a dangerous drug that acts as a stimulant and a psychedelic.

Effects of Molly Use

It affects users in many different ways – most significantly, it targets the brain. It induces serotonin, dopamine, and norepinephrine release, and can act directly on a number of receptors, including adrenaline and serotonin.

The serotonin system plays an important role in regulating mood, aggression, sexual activity, sleep, and sensitivity to pain. The excess release of serotonin by MDMA likely causes the users to experience euphoria (an exaggerated physical and psychological state).

However, by releasing large amounts of serotonin, MDMA causes the brain to become significantly depleted of this important neurotransmitter. This can, in turn, contribute to the negative behavioral after-effects that users often experience for several days after taking MDMA.

Other specific after-effects include lowered mood or even depression (comedown), increased anxiety, stress, and other negative emotions, residual feelings of empathy, emotional sensitivity, and a sense of closeness to others.

MDMA was found to produce an alteration of brain activity in cortical, limbic, and paralimbic structures. After being inhaled, eaten or parachuted (folded into a tissue and swallowed), the substance produces feelings of euphoria.

Some users reported heightened mood, increased extroversion, feelings of altered reality, and mild changes in perception. Feelings of “extroversion” linked with cerebral blood flow in the temporal cortex, amygdala, and orbitofrontal cortex were also reported.

In very rare cases, MDMA has been associated with serious neurological problems such as subarachnoid hemorrhage, intracranial bleeding, or cerebral infarction. Research on possible long-term adverse effects of MDMA has mainly focused on two areas: possible serotonergic neurotoxicity and psychiatric and behavioral problems that might result from MDMA use.

FAQ: All You Need To Know About Molly

1. What is Molly?

Molly is theorized to be short for “molecule” and is a slang term for MDMA (3,4-methylenedioxymethamphetamine) that comes in the form of pure MDMA crystals or powder (as opposed to pills). It is chemically the same thing as any other MDMA.

2. Is Molly illegal?

According to Barbara Carreno, a public affairs officer at the Drug Enforcement Administration (DEA), back in 2002 when Molly first made a name for itself, the DEA temporarily made it illegal and sent their recommendation to the HHS (Health and Human Services) that it be a “controlled substance.” After they conducted scientific studies, however, the DEA was overruled. Molly is currently legal in New York State under federal law. However, if Molly is tested and classified as an imitation-controlled substance, the user in possession of it can be charged under the Federal Analog Act.

3. Why do some users consider Molly “safer?”

In theory, Molly is high purity MDMA powder, which means unlike ecstasy, it’s not supposed to be cut with any fillers or other drugs. But according to Barbara Carreno, a public affairs officer at the DEA, Molly is an industrial chemical that was not made for human consumption, and you put your health and safety at risk when you use it.

4. What are Molly bath salts?

In some parts of the country, Molly bath salts are marketed as being similar to synthetic marijuana, called “spice” or “K2.” They’re labeled as bath products, but Internet commenters describe the experience of sniffing them as creating effects similar to “legal cocaine” or “legal speed.”

5. What is Molly’s plant food?

Molly’s plant food is a synthetic hallucinogenic amphetamine marketed as a “plant food” that contains ingredients that produce highs similar to Ecstasy. Molly’s plant food is usually purchased at a convenience store with label warning “not intended for human consumption.” The active ingredient is mephedrone, which is not a scheduled (DEA) drug, therefore making it legal.

6. What is mephedrone?

Mephedrone (4-methylmethcathinone) is a stimulant which is closely chemically related to amphetamines that have been found in Molly drug tests. Users report that mephedrone produces a similar experience to drugs like amphetamines, ecstasy or cocaine.

7. How will Molly affect users?

Molly affects users in several ways. According to the DEA, MDMA acts as a stimulant and a psychedelic that may cause hallucinogenic effects. After being inhaled, eaten or parachuted (folded into a tissue and swallowed) Molly leads in euphoria – a feeling of great happiness or well-being. It induces the release of the neurotransmitters serotonin, dopamine, and norepinephrine making the users feel elated, empathic and full of energy. However, negative effects have also been reported including but not limited to increased heart rate, blood pressure and temperature, blurred vision, nausea, increased anxiety, depression, etc.

8. What will happen if Molly is mixed with another drug?

Most of the time Molly is taken, it is mixed with another drug. The effects strongly depend on your tolerance, what drug it is mixed with, and how much of each drug is used.

9. How addictive is Molly?

Molly, as a term used to describe pure MDMA, is both hallucinogenic and a stimulant, but stimulant properties where the body can become dependent are most likely to lead to addiction. This type of dependency is what leads the body to crash after the drug wears off. Users will feel the urge to take another dose in order to get the stimulant effect again. If Molly is cut with another stimulant such as cocaine or amphetamine, the addictiveness increases.

10. Can you overdose on Molly?

Yes. Although death is a rare occurrence, it is possible to overdose. The typical recreational dosage ranges from 80 mg to 150 mg; 200 mg above is considered a heavy dosage. Going beyond that can result in a number of negative effects, most likely vomiting, headaches and dizziness.

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